Katherine L O'Brien Selected Research

Pneumococcal Infections

10/2021	Persistence of Immunity Following 2-Dose Priming with a 10-Valent Pneumococcal Conjugate Vaccine at 6 and 10 Weeks or 6 and 14 Weeks of Age in Nepalese Toddlers.
12/2019	Efficacy, safety and immunogenicity of a pneumococcal protein-based vaccine co-administered with 13-valent pneumococcal conjugate vaccine against acute otitis media in young children: A phase IIb randomized study.
10/2019	A public health evaluation of 13-valent pneumococcal conjugate vaccine impact on adult disease outcomes from a randomized clinical trial in the Netherlands.
1/2017	Estimated severe pneumococcal disease cases and deaths before and after pneumococcal conjugate vaccine introduction in children younger than 5 years of age in South Africa.
1/2017	Effectiveness of the 13-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in South African children: a case-control study.
2/2016	Global Burden of Neonatal Invasive Pneumococcal Disease: A Systematic Review and Meta-analysis.
4/2015	The serotype distribution among healthy carriers before vaccination is essential for predicting the impact of pneumococcal conjugate vaccine on invasive disease.
9/2014	Effectiveness of 7-valent pneumococcal conjugate vaccine against invasive pneumococcal disease in HIV-infected and -uninfected children in south africa: a matched case-control study.
1/2014	Systematic review of the effect of pneumococcal conjugate vaccine dosing schedules on vaccine-type invasive pneumococcal disease among young children.
1/2014	The differential impact of coadministered vaccines, geographic region, vaccine product and other covariates on pneumococcal conjugate vaccine immunogenicity.

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Katherine L O'Brien Research Topics

Disease

38	Pneumonia (Pneumonitis) 01/2022 - 05/2005
29	Pneumococcal Infections 10/2021 - 05/2003
7	Infections 01/2022 - 10/2002
6	Pneumococcal Pneumonia 01/2019 - 09/2009
5	Measles 01/2022 - 11/2015
5	Respiratory Sounds (Crackle) 01/2022 - 12/2015
5	Poliomyelitis (Polio) 01/2019 - 11/2015
4	Whooping Cough (Pertussis) 01/2022 - 05/2016
4	Diphtheria 01/2022 - 05/2016
4	Vaccine-Preventable Diseases 01/2021 - 05/2007
4	Otitis Media 12/2019 - 10/2003
3	Tetanus 01/2022 - 05/2016
3	Human Influenza (Influenza) 01/2020 - 02/2011
3	Respiratory Tract Infections (Respiratory Tract Infection) 12/2019 - 08/2002
2	Meningitis 11/2012 - 10/2003
2	Gastroenteritis 02/2012 - 01/2006
1	COVID-19 01/2022
1	Breakthrough Infections 01/2022
1	Pharyngitis (Sore Throat) 01/2019
1	Rheumatic Heart Disease (Rheumatic Heart Diseases) 01/2019
1	Paramyxoviridae Infections (Parainfluenza) 01/2019
1	Meningococcal Infections 01/2018
1	HIV Infections (HIV Infection) 01/2018
1	Infant Death 01/2018
1	Clinical Deterioration 06/2017
1	Bacterial Pneumonia 06/2017
1	Communicable Diseases (Infectious Diseases) 01/2017
1	Perinatal Death 12/2016
1	Hepatitis B 05/2016
1	Hypersensitivity (Allergy) 12/2015
1	Empyema 01/2014
1	Malnutrition (Nutritional Deficiencies) 04/2013
1	Meningococcal Meningitis 11/2012
1	Bacterial Meningitis 11/2012
1	Pneumococcal Meningitis (Streptococcus pneumoniae Meningitis) 11/2012
1	Bacteremia 03/2009
1	Respiratory Syncytial Virus Infections 10/2008
1	Intussusception 01/2006
1	Hypotension (Low Blood Pressure) 10/2003
1	Sickle Cell Anemia (Hemoglobin S Disease) 10/2003
1	Acute Chest Syndrome 10/2003
1	Alcoholism (Alcohol Abuse) 07/2003
1	Sepsis (Septicemia) 10/2002
1	Escherichia coli Infections 10/2002
1	Rubella (German Measles) 06/2002
1	Syphilis 06/2002

Drug/Important Bio-Agent (IBA)

55	VaccinesIBA 01/2022 - 05/2003
27	Conjugate VaccinesIBA 10/2021 - 05/2003
7	Anti-Bacterial Agents (Antibiotics)IBA 09/2021 - 10/2002
5	AntigensIBA 01/2019 - 01/2013
5	Polysaccharides (Glycans)IBA 01/2014 - 07/2003
4	C-Reactive ProteinIBA 01/2022 - 06/2017
4	Heptavalent Pneumococcal Conjugate Vaccine (Prevnar)IBA 03/2009 - 08/2003
3	Proteins (Proteins, Gene)FDA Link 12/2019 - 11/2012
3	Measles VaccineIBA 10/2019 - 05/2016
3	Pneumococcal Vaccines (Pneumococcal Polysaccharide Vaccine)IBA 06/2009 - 04/2004
2	Oxygen (Dioxygen)IBA 01/2021 - 06/2017
2	Immunoglobulin G (IgG)IBA 01/2019 - 10/2008
2	Hemagglutinins (Hemagglutinin)IBA 01/2017 - 02/2011
2	motavizumab (Numax)IBA 12/2016 - 12/2015
2	AntibodiesIBA 12/2016 - 03/2009
1	COVID-19 VaccinesIBA 01/2022
1	Sulfamethoxazole Drug Combination Trimethoprim (Co-Trimoxazole)FDA LinkGeneric 09/2021
1	Respiratory Syncytial Virus VaccinesIBA 01/2021
1	Immunoglobulins (Immunoglobulin)IBA 01/2019
1	Bacterial VaccinesIBA 10/2017
1	DNA (Deoxyribonucleic Acid)IBA 06/2017
1	Coloring Agents (Dyes)IBA 06/2017
1	N-Acetylmuramoyl-L-alanine Amidase (Autolysin)IBA 06/2017
1	Nucleic AcidsIBA 06/2017
1	SolutionsIBA 06/2017
1	pertussis toxoidIBA 01/2017
1	Combined VaccinesIBA 01/2017
1	pertactin FDA Link 01/2017
1	Monoclonal AntibodiesIBA 12/2015
1	ZincIBA 04/2013
1	Rotavirus VaccinesIBA 02/2012
1	23-valent pneumococcal capsular polysaccharide vaccineIBA 07/2011
1	Neutralizing AntibodiesIBA 10/2008
1	Glycoproteins (Glycoprotein)IBA 10/2008
1	Complement System Proteins (Complement)IBA 01/2008
1	Polyvinyl Chloride (PVC)IBA 10/2003
1	Sickle HemoglobinIBA 10/2003
1	Penicillins (Penicillin)FDA Link 10/2003
1	Hemoglobins (Hemoglobin)IBA 10/2003
1	Ampicillin (Omnipen)FDA LinkGeneric 10/2002
1	EnzymesIBA 08/2002
1	Hepatitis B Surface Antigens (HBsAg)FDA Link 06/2002

Therapy/Procedure

3	Stethoscopes 01/2022 - 01/2017
1	Prenatal Care (Care, Prenatal) 12/2016
1	Therapeutics 04/2012
1	Contraindications 04/2012
1	Ambulatory Care (Outpatient Care) 01/2006
1	Antibiotic Prophylaxis 10/2003